Biocompatibility and cytotoxicity in vitro of surface-functionalized drug-loaded spinel ferrite nanoparticles

• Sadaf Mushtaq,
• Khuram Shahzad,
• Tariq Saeed,
• Anwar Ul-Hamid,
• Bilal Haider Abbasi,
• Nafees Ahmad,
• Waqas Khalid,
• Muhammad Atif,
• Zulqurnain Ali and
• Rashda Abbasi

Beilstein J. Nanotechnol. 2021, 12, 1339–1364, doi:10.3762/bjnano.12.99

• Department of Physics, Functional Materials Lab, Air University, Sector E-9, Islamabad, Pakistan Core Research Facilities, King Fahd University of Petroleum & Minerals, Dhahran 31261, Saudi Arabia 10.3762/bjnano.12.99 Abstract In this study, poly(isobutylene-alt-maleic anhydride) (PMA)-coated spinel ferrite

• studies; magnetic spinel ferrite nanoparticles; methotrexate; poly(isobutylene-alt-maleic anhydride); Introduction Cancer is the second leading cause of death and, as such, it is a global health concern [1]. It is caused by uncontrolled cell proliferation, reduced cell death rate, or both [2

• hydrophobic NPs was achieved by the functionalization with an amphiphilic brush copolymer, poly(isobutylene-alt-maleic anhydride) (PMA) implanted with dodecylamine, which provides biocompatibility, colloidal stability, and hydrophilicity [22]. It is composed of hydrophobic side chains and the backbone of

Involvement of two uptake mechanisms of gold and iron oxide nanoparticles in a co-exposure scenario using mouse macrophages

• Dimitri Vanhecke,
• Dagmar A. Kuhn,
• Dorleta Jimenez de Aberasturi,
• Sandor Balog,
• Ana Milosevic,
• Dominic Urban,
• Diana Peckys,
• Niels de Jonge,
• Wolfgang J. Parak,
• Alke Petri-Fink and
• Barbara Rothen-Rutishauser

Beilstein J. Nanotechnol. 2017, 8, 2396–2409, doi:10.3762/bjnano.8.239

• ), the NPs are referred to as FeOxNPs. Due to the short exposure and the similar surface chemistry the precise stoichiometry of the FeOxNPs is assumed to be not of major relevance in this present study. The two NP types coated with poly(isobutylene-alt-maleic anhydride)-graft-dodecylamine (PMA), i.e

Effects of surface functionalization on the adsorption of human serum albumin onto nanoparticles – a fluorescence correlation spectroscopy study

• Pauline Maffre,
• Stefan Brandholt,
• Karin Nienhaus,
• Li Shang,
• Wolfgang J. Parak and
• G. Ulrich Nienhaus

Beilstein J. Nanotechnol. 2014, 5, 2036–2047, doi:10.3762/bjnano.5.212

• desorption of HSA, that is, non-equilibrium binding (unpublished data). Considering that the ≈3 nm thick [30] polymer shell consists of dodecylamine crosslinked by poly(isobutylene alt-maleic anhydride) [55], it is highly likely that some HSA molecules get entangled in the polymeric meshwork and may even

Characterization of protein adsorption onto FePt nanoparticles using dual-focus fluorescence correlation spectroscopy

• Pauline Maffre,
• Karin Nienhaus,
• Faheem Amin,
• Wolfgang J. Parak and
• G. Ulrich Nienhaus

Beilstein J. Nanotechnol. 2011, 2, 374–383, doi:10.3762/bjnano.2.43

• surrounding NPs. Experimental Sample preparation FePt NP cores were synthesized according to published protocols [45] and coated with an amphiphilic polymer synthesized from dodecylamine and poly(isobutylene-alt-maleic anhydride). They carry carboxylic acid groups on their surfaces, making them water-soluble